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Title: Pancreatic polypeptide cells of rat pancreas after chronic ethanol feeding
Authors: Koko, Vesna
Todorovic, Vera
Drndarevic, Neda
Glisic, Radmila
Nedeljkovic, Miroslava
Nikolic, Anna
Issue Date: May-2001
Publisher: NISCAIR-CSIR, India
Abstract: Male Wistar rats, (2 months old) were randomly divided into two groups according to the diet offered (C-control and E-ethanol treated rats). Final body weight was significantly increased but pancreatic weight as a percentage of body weight was decreased in ethanol treated rats. Volume density, number of pancreatic poly peptide (PP)-cells per islet and per µm2 of islet were significantly increased. PP-cells were abundant and occupied the whole periphery of islets in the splenic part of the pancreas. Those cells showed strong immunopositivity. At the ultrastructural level PP granules had predominantly less electron density. The mean diameter of PP granules was significantly increased and the number of granules of larger diameter was greater in the E group of rats, than in the controls.
Page(s): 416-424
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.39(05) [May 2001]

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