Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/23572
Title: Mentha piperita (Linn) leaf extract provides protection against radiation induced alterations in intestinal mucosa of Swiss albino mice
Authors: Samarth, R M
Saini, M R
Maharwal, J
Dhaka, A
Kumar, Ashok
Issue Date: Nov-2002
Publisher: NISCAIR-CSIR, India
Abstract: Intestinal protection in mice against radiation injury by M. piperita (1 g/kg body weight/day) was studied from day 1 to day 20 after whole body gamma irradiation (8 Gy). Villus height, goblet cells/villus section, total cells, mitotic cells and dead cells/crypt section in the jejunum arc good parameters for the assessment of radiation damage. There was significant decrease in the villus height, number of  total cells and mitotic cells/crypt section, whereas goblet cells and dead cells showed significant increase after irradiation. Mentha pretreatment resulted in a significant increase in villus height, total cells and mitotic cells, whereas goblet cells and dead cell s showed a significant decrease from respective irradiated controls at each autopsy day. The results suggest that Mentha pretreatment provides protection against radiation induced alterations in intestinal mucosa of Swiss albino mice.
Page(s): 1245-1249
URI: http://hdl.handle.net/123456789/23572
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.40(11) [November 2002]

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