Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/23538
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dc.contributor.authorSheema-
dc.contributor.authorKaleem, M-
dc.contributor.authorBano, Bilqees-
dc.date.accessioned2013-11-13T08:45:20Z-
dc.date.available2013-11-13T08:45:20Z-
dc.date.issued2004-07-
dc.identifier.issn0975-1009 (Online); 0019-5189 (Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/23538-
dc.description691-697en_US
dc.description.abstractPost fish oil(n-3 fatty acids) treatment (5mg/kg/day for 12 days) was effective in bringing the reversal of tobramycin (160mg/kg/day,ip for 12 days) induced nephrotoxicity in albino rats as was evident by normal urea, creatinine, cholesterol and inorganic phosphate levels in the serum of the treatment group compared with group receiving tobramycin only. The return of normal levels of alkaline and acid phosphatase in kidney homogenates of post fish oil treatment group also indicated the beneficial effect of dietary n-3 fatty acids(fish oil) more than n-6 fatty acids(olive oil).The results suggest that oral supplements of dietary n-3 fatty acids (fish oil) for nearly two weeks after tobramycin exposure is more beneficial than n-6 fatty acids (olive oil) as it results in reversal of nephrotoxicity induced by tobramycin.en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.relation.ispartofseriesInt. Cl7 A61Ken_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJEB Vol.42(07) [July 2004]en_US
dc.subjectAminoglycosidesen_US
dc.subjectTobramycinen_US
dc.subjectNebramycinen_US
dc.subjectNephrotoxicityen_US
dc.subjectn-3 fatty acidsen_US
dc.subjectFish oilen_US
dc.subjectn-6 fatty acidsen_US
dc.subjectOlive oilen_US
dc.subjectUreaen_US
dc.subjectCreatinineen_US
dc.titleEffect of dietary n-3 and n-6 fatty acids on tobramycin induced nephrotoxicityen_US
dc.typeArticleen_US
Appears in Collections:IJEB Vol.42(07) [July 2004]

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