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Title: Effect of lupeol isolated from Crataeva nurvala Buch.- Ham. stem bark extract against free radical induced nephrotoxicity in rats
Authors: Shirwaikar, Annie
Setty, Manjunath M
Bommu, Praveen
Krishnanand, B
Keywords: Lupeol;Crataeva nurvala;Nephrotoxicity;Rats;Free radical
Issue Date: Jul-2004
Publisher: NISCAIR-CSIR, India
IPC Code: Int. Cl7 A61P
Abstract: Lupeol. isolated from Crataeva nurvala stem bark in doses 40 and 80 mg/kg body weight. po. for 10 days, decreased the concentration of blood urea nitrogen, creatinine and lipid peroxidation and increased glutathione and catalase activities in cisplatin (5 mg/kg body weight. ip) induced nephrotoxicity in rats. The increased glutathione and catalase activities are indicative of antioxidant properties of lupeol.
Page(s): 686-690
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.42(07) [July 2004]

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