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IJBT Vol.07(4) [October 2008] >


Title: The stem cell in the umbilical cord blood is not related to volume and nucleated cell count
Authors: Mahantappa, A
Banik, Avijit
Shivshankar, Jyothsna
Rao, S G A
Keywords: Autologous banking
CD 34⁺ cells
Haematopoietic stem cells
Umbilical cord blood
Issue Date: Oct-2008
Publisher: CSIR
Abstract: The percent CD 34⁺ cells in umbilical cord tremendously var-ied from sample to sample. Study conducted on 100 cryopre-served samples for their volume, nucleated cell count and CD 34⁺ cell count showed no correlation between the three. Correlation study between volume and nucleated cell count showed poor cor-relation, where as correlation between volume and CD 34⁺, nucle-ated cell count and CD 34⁺ cell count showed no/negative correla-tion. Graphical representation of volume vs. nucleated cell count, volume vs. CD 34⁺ cell count, and nucleated cell count vs. CD 34⁺ cell count show the same results. These results have important bearing in umbilical cord blood banking, since sample accep-tance/rejection at present is based only on volume of cord blood collected, which instead should be based on the number of CD 34⁺ stem cells.
Page(s): 547-549
ISSN: 0972-5849
Source:IJBT Vol.07(4) [October 2008]

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