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Indian Journal of Biotechnology (IJBT) >
IJBT Vol.07 [2008] >
IJBT Vol.07(4) [October 2008] >
| Title: | The stem cell in the umbilical cord blood is not related to volume and nucleated cell count |
| Authors: | Mahantappa, A
Banik, Avijit
Shivshankar, Jyothsna
Rao, S G A |
| Keywords: | Autologous banking
CD 34⁺ cells
Haematopoietic stem cells
Umbilical cord blood |
| Issue Date: | Oct-2008 |
| Publisher: | CSIR |
| Abstract: | The percent CD 34⁺ cells in umbilical cord tremendously var-ied from sample to sample. Study conducted on 100 cryopre-served samples for their volume, nucleated cell count and CD 34⁺ cell count showed no correlation between the three. Correlation study between volume and nucleated cell count showed poor cor-relation, where as correlation between volume and CD 34⁺, nucle-ated cell count and CD 34⁺ cell count showed no/negative correla-tion. Graphical representation of volume vs. nucleated cell count, volume vs. CD 34⁺ cell count, and nucleated cell count vs. CD 34⁺ cell count show the same results. These results have important bearing in umbilical cord blood banking, since sample accep-tance/rejection at present is based only on volume of cord blood collected, which instead should be based on the number of CD 34⁺ stem cells. |
| Page(s): | 547-549 |
| ISSN: | 0972-5849 |
| Source: | IJBT Vol.07(4) [October 2008]
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