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Title: Solid state cultivation of Curvularia lunata for transformation of rifamycin B to S
Authors: Rasalkar, A A
Salunke, B K
Sayyed, R Z
Chaudhari, A B
Chincholkar, S B
Issue Date: Aug-2002
Publisher: NISCAIR-CSIR, India
Abstract: Biotransformation of rifamycin B to rifamycin S using two strains of C. lunata namely NCIM 716 and NMU grown on various solid substrates viz., grass, paper, jowar/wheat straw, bran and bagasse was studied. Almost complete biotransformation efficiency of rifamycin B at 0.06mM concentration was observed within 24 hr. Among these two strains, C. lunata NMU showed 90% of biotransformation and higher rate of cellulose utilization on solid substrates vis-à-vis reference strain. Cellulase activity of both strains was also studied for exoglucanase, endoglucanase and β-glucosidase. Column bioreactor studies with bagasse revealed further improvement in biotransformation efficiency of C. lunota NMU.
Page(s): 930-933
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.40(08) [August 2002]

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