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Title: Influence of aluminium on neurotoxicity of lead in adult male albino rats
Authors: Shakoor, A
Gupta, P K
Kataria, M
Keywords: Acetylcholinesterase;Aluminium, Brain;Lead toxicity;Malondialdehyde;Neurotoxicity
Issue Date: Jun-2003
Publisher: NISCAIR-CSIR, India
Abstract: Influence of aluminium on neurotoxicity of lead was studied in male albino rats. Aluminium enhanced the net deposition of lead in brain. This was further substantiated by higher levels of malondialdehyde (MDA), and lower activities of acetylcholinesterase enzyme in the brain homogenates of the rats treated with both lead and aluminium as compared to those of rats treated with lead only. In lead plus aluminium treated animals, a significant neurological deficit was observed when the animals were subjected to rota-rod, traction performance (TP) and tail immersion tests.
Page(s): 587-591
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.41(06) [June 2003]

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