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Title: Selenium, a versatile trace element: Current research implications
Authors: Bansal, M P
Kaur, Parminder
Keywords: Anticarcinogenesis;Cardiovascular system;Glutathione peroxidase;Immunosuppression;Male reproduction;Selenium;Selenoproteins
Issue Date: Dec-2005
Publisher: NISCAIR-CSIR, India
Abstract: Selenium (Se), a trace element, has evolved from its toxic properties to an essential element. Se was known a potent antioxidant through glutathione peroxidase (selenium being part of this molecule). Later, many other selenium-binding proteins were discovered and their functions were tried to be known with unsuccessful results in many cases. Se is known to be involved in carcinogenesis, immune function, male reproduction, cardiovascular diseases etc. The specific mechanism of the involvement of the element is still not known. Recent research with application of modern research tools viz. bioinformatics, cDNA microarray and transgenesis have revealed the mechanism of selenium involvement in various processes. This review highlights mysterious and useful roles of selenium in biological processes.
Page(s): 1119-1129
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.43(12) [December 2005]

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