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dc.contributor.authorManjunatha, B K-
dc.contributor.authorVidya, S M-
dc.contributor.authorDhiman, Promilla-
dc.contributor.authorPallavi, R-
dc.contributor.authorMankani, K L-
dc.identifier.issn0975-1009 (Online); 0019-5189 (Print)-
dc.description.abstractMethanol and aqueous leaf extracts of L. hirta demonstrated hepatoprotective activity against carbon tetrachloride induced liver damage in rats. The parameters studied were serum total bilirubin, total protein, alanine transaminase, aspartate transaminase and alkaline phosphatase activities. The hepatoprotective activity was also supported by histopathological studies of liver tissue. Results of the biochemical studies of blood samples of CCl4 treated animals showed significant increase in the levels of serum markers and decrease in total protein level reflecting the liver injury caused by CCl4. Whereas blood samples from the animals treated with methanol and aqueous leaf extracts showed significant decrease in the levels of serum markers and increase in total protein indicating the protection of hepatic cells. The results revealed that methanol leaf extract followed by aqueous extract of L. hirta could afford significant protection against CCl4 induced hepatocellular injury.en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJEB Vol.43(08) [August 2005]en_US
dc.subjectHepatoprotective activityen_US
dc.subjectLeaf extracten_US
dc.subjectLeucas hirtaen_US
dc.titleHepatoprotective activity of Leucas hirta against CCl4 induced hepatic damage in ratsen_US
Appears in Collections:IJEB Vol.43(08) [August 2005]

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