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Title: Hypolipidemic effect of methanolic extract of Dolichos biflorus Linn. in high fat diet fed rats
Authors: Muthu, A Kottai
Sethupathy, S
Manavalan, R
Karar, P K
Keywords: Dolichos biflorus;Hypolipidemic effect;Methanolic extract;Rat
Issue Date: Jun-2005
Publisher: NISCAIR-CSIR, India
IPC Code: Int. Cl7 A61P
Abstract: High fat diet fed rats showed significant increased levels of plasma and tissue total cholesterol, triglycerides, free fatty acids, phospholipids, plasma LDL cholesterol and decreased level of plasma H DL cholesterol. Methanolic extract o f D.biflorus administration to high fat diet fed rats showed near to normal levels of the above lipids in plasma and tissues. Higher dose of the extract (400 mg/kg body weight) showed comparable results with standard drug atorvastatin. It is concluded that the methanolic extract of D. biflorus possesses hypolipidemic activity in high fat diet fed rats.
Page(s): 522-525
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.43(06) [June 2005]

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