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Title: Lysosomal stability in Oreochromis mossambicus (Peters) on exposure to surfactants
Authors: Bindu, PC
Philip, Babu
Chandran, R Vinu
Keywords: Lysosomes;Oreochromis mossambicus;Surfactant toxicity
Issue Date: Jan-2005
Publisher: NISCAIR-CSIR, India
Abstract: The three commonly used surfactants viz. anionic sodium dodecyl sulfate (SDS), cationic cetyl tri methyl ammonium bromide (CTAB) and non-ionic triton X-100 were toxic even at sublethal levels (1 ppm for 30 days) to O. mossambicus. Lysosomal stability index (LSI) was lowest in triton-exposed animals in vitro. in vivo, CTAB was the most toxic. SDS, the anionic surfactant was the least toxic. The possible role of surfactant structure, critical micellar concentration (CMC) and metabolism in influencing the toxicity is discussed and mechanism of action via membrane lipid peroxidation is suggested.
Page(s): 96-99
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.43(01) [January 2005]

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