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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.47B [2008] >
IJC-B Vol.47B(10) [October 2008] >
| Title: | Synthesis and β-adrenergic blocking activity of naphthyloxypropylamines |
| Authors: | Vattipalli, Ramya
Shirodkar, Prabhakar Y
Somani, Rakesh R
Kadam, Vilasrao J |
| Keywords: | Synthesis
β-adrenergic blockers
Aryloxypropanolamines |
| Issue Date: | Oct-2008 |
| Publisher: | CSIR |
| Abstract: | A series of 1-isopropylamino-3-(3'-substituted-2'-naphthyloxy)-2-propanols have been synthesized and their structures have been confirmed by spectral analysis. All the derivatives have shown β-adrenergic blocking effect when tested on perfused frog heart. Compound 4e exhibited 100% blockade of adrenaline response. |
| Page(s): | 1587-1590 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.47B(10) [October 2008]
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