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Title: Synthesis and biological evaluation of 2-aminobenzothiazole derivatives
Authors: Srivastava, S D
Sen, J P
Keywords: 2-Aminobenzothiazole;Thiazolidinone;Chloroacetyl chloride;Thioglycolic acid;Antimicrobial activity
Issue Date: Oct-2008
Publisher: CSIR
Abstract: As a part of systematic investigation of synthesis and biologically active compounds of 2-amino benzothiazoles, several new [(2"-substituted aryl)-4"-oxo-1",3"-thiazolidine-3"-iminoacetyl]-2-aminobenzothiazole 5 and [(5"-arylidene-2"-substituted aryl-4"-oxo-1",3"-thiazolidine)-3"-iminoacetyl]-2-aminobenzothiazole 6 from 2-aminobenzothiazole have been synthesized. All the synthesized products are evaluated for their antibacterial activity against Bacillus substilis, Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus and antifungal activity against Aspergillus niger, Aspergillus flavus, Fusarium oxisporum and Trichoderma viride. The structures of all the synthesized compounds have been determined by spectral and chemical methods.
Page(s): 1583-1586
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.47B(10) [October 2008]

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