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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.47B [2008] >
IJC-B Vol.47B(10) [October 2008] >
| Title: | Synthesis and biological evaluation of 2-aminobenzothiazole derivatives |
| Authors: | Srivastava, S D
Sen, J P |
| Keywords: | 2-Aminobenzothiazole
Thiazolidinone
Chloroacetyl chloride
Thioglycolic acid
Antimicrobial activity |
| Issue Date: | Oct-2008 |
| Publisher: | CSIR |
| Abstract: | As a part of systematic investigation of synthesis and biologically active compounds of 2-amino benzothiazoles, several new [(2"-substituted aryl)-4"-oxo-1",3"-thiazolidine-3"-iminoacetyl]-2-aminobenzothiazole 5 and [(5"-arylidene-2"-substituted aryl-4"-oxo-1",3"-thiazolidine)-3"-iminoacetyl]-2-aminobenzothiazole 6 from 2-aminobenzothiazole have been synthesized. All the synthesized products are evaluated for their antibacterial activity against Bacillus substilis, Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus and antifungal activity against Aspergillus niger, Aspergillus flavus, Fusarium oxisporum and Trichoderma viride. The structures of all the synthesized compounds have been determined by spectral and chemical methods. |
| Page(s): | 1583-1586 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.47B(10) [October 2008]
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