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Title: Facile ZrCl₄ promoted four-component coupling one-pot synthesis of polyhydroquinoline derivatives through unsymmetric Hantzsch reaction
Authors: Reddy, Ch Sanjeeva
Raghu, M
Keywords: Polyhydroquinolines
Four-component coupling
One-pot conversion
ZrCl₄ catalyst
Issue Date: Oct-2008
Publisher: CSIR
Abstract: ZrCl₄ catalyzed efficient unsymmetric Hantzsch reaction via four-component coupling reaction of aldehydes, dimedone, ethyl acetoacetate and ammonium acetate at ambient temperature is described as the preparation of polyhydroquinoline derivatives. The process presented here is an operationally simple, economic, environmentally benign and provides excellent yield. Furthermore, the catalyst can be recovered conveniently and reused efficiently.
Description: 1578-1582
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.47B(10) [October 2008]

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