Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/22568
Title: Mechanistic investigation of oxidation of 6-deoxyhexoses by sodium N-chloro-p-toluenesulfonamide in alkaline medium
Authors: Rangappa, K S
Raghavendra, M P
Anitha, N
Gowda, D Channe
Issue Date: Nov-2000
Publisher: NISCAIR-CSIR, India
Abstract: The kinetics and mechanism of oxidation of L-fucose and L-rhamnose by chloramine-T (CAT) in alkaline medium has been investigated at 40°C. The rate of the reaction is first order with respect to [sugar][CAT] and [hydroxide ion]. The reaction rate is influenced by a change in ionic strength of the medium and the dielectric effect has been found to be negative. Proton inventory studies have been made in H2O- D2O mixtures. Activation parameters have been determined from the Arrhenius plots. HPLC and GLC-MS analyses of the products indicate that 6-deoxyhexoses are oxidized to a mixture of aldonic acids. The proposed mechanism is consistent with the observed results.
Page(s): 836-841
URI: http://hdl.handle.net/123456789/22568
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.39B(11) [November 2000]

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