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dc.contributor.authorBansal, Ekta-
dc.contributor.authorSrivastava, V K-
dc.contributor.authorKumar, Ashok-
dc.identifier.issn0975-0983(Online); 0376-4699(Print)-
dc.description.abstractVarious 3-(2-arylideneaminothiazol-4-yl)indoles 3a-e and 3-(2-arylideneaminooxazol-4-yl)indoles 3a'-e' on diazotisation with aniline afford 3-[2-(1'-phenyl-3′-substituted-aryl-formazan-4′-yl)thiazol-4-yl] indoles 4a-e and 3-[2-(1'-substituted-phenyl-3′-substituted aryl-formazan-4′-yl)oxazol-4-yl]indoles 4a' -e' respectively. All the compounds have shown interesting antiinflammatory activity in carrageenan induced oedema in rats at 50 mg/kg p.o. The most active compound in the series is 3-[2-(o-methoxybenzylidene) aminothiazol-4-yl] indole which has shown higher anti-inflammatory activity and lower ulcerogenic property than phenylbutazone.en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJC-B Vol.39B(05) [May 2000]en_US
dc.titleSynthesis of some new formazanyl-thiazolyl-indoles and formazanyl-oxazolyl-indoles as inflammation inhibitorsen_US
Appears in Collections:IJC-B Vol.39B(05) [May 2000]

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