Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/22394
Title: Synthesis and antimicrobial activity of N-(substitutedphenyl)-N'-[1,2,3,4-tetrahydro-2-oxido-1,3,2-benzodiazaphosphorine-2-yl] ureas
Authors: Rao, L Nagaprasada
Reddy, C Devendranath
Reddy, B Sankar
Issue Date: Sep-2001
Publisher: NISCAIR-CSIR, India
Abstract: N-(Substitutedphenyl)-N'-(1,2,3,4-tetrahydro-2-oxido-1 ,3,2-benzodiazaphosphorine-2-yl] ureas 5 which are substituted ureas of the type RR'P(O)NHC(O)NR"R"' have been synthesized from reactions of 2-aminobenzylamine  2 with chlorides of arylcarbamidophos phoric acids 4 in the presence of triethylamine at 40-45°C. IR , 1H and 31P NMR and mass spectra are recorded and analysed. The title compounds have been screened for their antifungal and antibacterial activities. All of these compounds exhibit significant activity in the assays.
Page(s): 817-821
URI: http://hdl.handle.net/123456789/22394
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.40B(09) [September 2001]

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