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|Title:||Synthesis and antimicrobial activity of N-(substitutedphenyl)-N'-[1,2,3,4-tetrahydro-2-oxido-1,3,2-benzodiazaphosphorine-2-yl] ureas|
|Authors:||Rao, L Nagaprasada|
Reddy, C Devendranath
Reddy, B Sankar
|Abstract:||N-(Substitutedphenyl)-N'-(1,2,3,4-tetrahydro-2-oxido-1 ,3,2-benzodiazaphosphorine-2-yl] ureas 5 which are substituted ureas of the type RR'P(O)NHC(O)NR"R"' have been synthesized from reactions of 2-aminobenzylamine 2 with chlorides of arylcarbamidophos phoric acids 4 in the presence of triethylamine at 40-45°C. IR , 1H and 31P NMR and mass spectra are recorded and analysed. The title compounds have been screened for their antifungal and antibacterial activities. All of these compounds exhibit significant activity in the assays.|
|Appears in Collections:||IJC-B Vol.40B(09) [September 2001]|
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