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|Title:||Novel triheterocyclic systems by Mannich reaction on 3-arylsydnones : Synthesis of 3-aryl-4-[2'-(8′′-hydroxy-7"-quinolinylmethylamino)-thiazol-4'-yl]sydnones and 3-aryl-4-[2′-(3′′-acetyl-2"-hydroxybenzylamino)-thiazol-4'-yl] sydnones as possible antimicrobial agents|
|Authors:||Mallur, Shanta G|
Badami, Bharati V
|Abstract:||3-Aryl-4 (2'-aminothiazol-4'-yl) sydnones 2a-m when subjected to Mannich reaction with 8-hydroxyquinoline give the triheterocyclic Mannich bases 3a-m. Similar reaction with orthohydroxy acetophenone resulted in the formation of the methylamino derivatives 4a-m. All these compounds have been evaluated for antimicrobial activity, while compounds 3a-m have been screened for their antitubercular activity also.|
|Appears in Collections:||IJC-B Vol.40B(08) [August 2001]|
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