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dc.contributor.authorMohan, Jag-
dc.identifier.issn0975-0983(Online); 0376-4699(Print)-
dc.description.abstract3,3-Diethyl-2H,4H-thiazolo[3,2-b]-s-tetrazin-6(7 H)-one 2, 3,3-diethyl -2H,4H -6, 7 -dihydrothiazolo[3,2-b]-s-tetrazine hydrobromide 4 and 6-aryl-3, 3-diethyl-2H, 4H-thiazolo[3,2-b]-s-tetrazine hydrobromide 5 have been synthesised by the reaction of 6,6-diethyl- l, 2, 4, 5-tetrahydro-s-tetrazin-3-thione 1 with chloroacetic acid, 1,2-dibromoethane and α-haloketones, respectively. 7-Arylidene-3,3-diethyl-2H, 4H -thiazolo[3,2-b]-s-tetrazin-6(7H)-ones 3 have been prepared either by the condensation of 2 with aldehyde or in a single step by the reaction of 1 with ethyl chloroacetate and aldehydes in the presence of pyridine and piperidine. Condensation of 3 with 2,4-dinitrophenylhydrazine in the presence of anhydrous sodium acetate furnishes 7,8-diaryl-2H, 4H -trans-8,8a dihydropyrazolo [3',4':4,5]thiazolo[3,2,-b]-s-tetrazines 6. The antibacterial and antifungal activity of some of the compounds have also been evaluated.en_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJC-B Vol.40B(07) [July 2001]en_US
dc.titleHeterocyclic systems containing bridgehead nitrogen atom : Synthesis, stereochemistry and evaluation of biological activity of thiazolo [3 ,2-b]-s-tetrazines and trans-dihydropyrazolo [3',4' :4,5]thiazolo[3,2-b]-s-tetrazinesen_US
Appears in Collections:IJC-B Vol.40B(07) [July 2001]

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