Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/22249
Title: Screening of natural products for new leads as inhibitors of IҡBα kinase: 2-Hydroxy-6- substituted benzoic acids from plant extracts
Authors: Ramakrishna, N V S
Jain, A K
Kota, S
Kumar, E K S Vijaya
Kalakoti, S
Gupte, R D
Panicker, R B
Vadlamudi, R V S V
Issue Date: Apr-2001
Publisher: NISCAIR-CSIR, India
Abstract: 2-Hydroxy-6-pentadecylbenzoic acidl 1, 2-hydroxy-6-(8,11-pentadecadienyl)benzoic acid2 2 and 2-hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid2 3 have been isolated from the crude extracts of plants from Anacardiaceae family by bioactive guided purification. Compound 1 has been isolated from pet. Ether extract of twigs of Rhus semialata and 2, 3 from CH2Cl2-MeOH (1:1) extract of the dried pericarp of the fruits of Anacardium occidentale. All the three compounds show good IҡBα kinase inhibitory activity.
Page(s): 345-347
URI: http://hdl.handle.net/123456789/22249
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.40B(04) [April 2001]

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