Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/22230
Title: Synthesis and pharmacological studies of 1-p-nitrobenzoyl-3-(3-substituted-2-hydroxypropyloximino) indole-2,3-diones
Authors: Padhy, A K
Panda, P K
Sahu, S K
Misro, P K
Issue Date: Mar-2001
Publisher: NISCAIR-CSIR, India
Abstract: Sodium salt of 3-oximino indole-2,3-dione on reaction with epichlorohydrin in N,N'-dimeth ylformamide gives 3-(2,3-epoxypropyloximino) indole-2,3-dione 2. Compound 2 on reaction with diverse secondary amines yields corresponding Mannich bases 3a-e, which on benzoylation furnish 4a-e. The synthetic benzoyl derivatives of 4a-e have been screened for their pharmacological activities.
Page(s): 258-261
URI: http://hdl.handle.net/123456789/22230
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.40B(03) [March 2001]

Files in This Item:
File Description SizeFormat 
IJCB 40B(3) 258-261.pdf714.68 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.