Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/22151
Title: Synthesis of pyrazolines and cyanopyridines as potential antimicrobial agents
Authors: Bhatt, Akhil H
Parekh, H H
Parikh, Khyati A
Parikh, A R
Issue Date: Jan-2001
Publisher: NISCAIR-CSIR, India
Abstract: 3,3'-Bis-(4-acetophenylaminosulphonyl)benzophcnone 1 on condensation with various aldehydes yields chalcones 2a-p which on cyclization with hydrazine hydrate and malononitrile furnishes the corresponding 3,3'-bis-(5-aryl-1 H/acetyl-pyrazolin- 3-yl-4-phenylaminosulphonyl)benzophenones 3a-p,3'a-p and 3,3'-bis-(2-amino-3-cyano-4-aryl pyridin-6-yl-4-phenylaminosulphonyl)benzophenones 4a-p. The structure of the compounds have been confirmed from elemental analyses, IR, 1H NMR and mass spectral data. All the products have been evaluated for their in vitro growth inhibitory activity against different microbes.
Page(s): 57-61
URI: http://hdl.handle.net/123456789/22151
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.40B(01) [January 2001]

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