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Title: Biotransformations, antibacterial evaluations of the sesquiterpenoids and diterpenoids+
Authors: Rao, M Rama
Venkatesham, U
Sridevi, K V
Reddy, P Srinivasa
Jamil, Kaiser
Venkateswarlu, Y
Issue Date: Jul-2002
Publisher: NISCAIR-CSIR, India
Abstract: Incubation of 6β,7β-epoxy-4β-hydroxyguaian-10-ene 1 with fungus Aspergillus niger affords 4β, 13-dihydroxyguaian-6, 10-diene 4 and 4β, 12-dihydroxy-guaian-6,10-diene 5, whereas with a plant pathogenic fungus Glomerella cingulata yields exclusively compound 4. In separate experiments incubation of (EEE)-7β,8β-epoxy-1-isopropyl-4,8,12-trimethylcyclotetradeca-1,3, 11-triene 2 and deoxosarcophine 3 with Aspergillus niger afford exclusively (EEE)-7β,8α-dihydroxy-1-isopropyl-4,8,12-trimethylcyclotetradeca-1 ,3, 11-triene 6 and 9β-hydroxydeoxosarcophine 7, respectively. The structures of compounds 4, 5, 6 and 7 have been confirmed by spectral data. Antibacterial evaluations of these compounds have been conducted.
Page(s): 1472-1476
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.41B(07) [July 2002]

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