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Title: Regio- and stereoselective synthesis of isoxazolines via cycloaddition reactions using pregnenolone as chiral auxiliary
Authors: Sharma, Utpal
Bora, Utpal
Chetia, Apurba
Boruah, Romesh C
Sandhu, Jagir Singh
Issue Date: May-2002
Publisher: NISCAIR-CSIR, India
Abstract: The asymmetric 1,3-dipolar cycloaddition reaction of nitrile oxides 2a-b to olefins 1a-c has been acccomplished by employing pregnenol one as chiral auxiliary. The optically pure 3-aryl-5-isoxazoline esters 9 are obtained from the major diastereomer in good yield.
Page(s): 1012-1014
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.41B(05) [May 2002]

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