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Title: A novel process for synthesis of Atovaquone
Authors: Roy, Bhairab N
Singh, Girij P
Lathi, Piyush S
Agrawal, Manoj K
Mitra, Rangan
Trivedi, Anurag
Keywords: Atovaquone;Cis-atovaquone;1-tetralone;Mukaiyama aldol reaction
Issue Date: Oct-2013
Publisher: NISCAIR-CSIR, India
Abstract: A stereospecific efficient process for synthesis of atovaquone i.e. trans-2-[4-(4-chlorophenyl)cyclohexyl ]-3-hydroxy-1,4-naphthalenedione and its cis isomer from commercially available raw materials such as a-tetralone and 4-(4-chlorophenyl)cyclohexanone is described.
Page(s): 1299-1312
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.52B(10) [October 2013]

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