Please use this identifier to cite or link to this item:
|Title:||An unexpected synthesis of 1H perimidin — X-ray crystal structure of 1H-perimidine hydrochloride dihydrate|
|Authors:||Ng, Seik W|
Drew, Michael G B
Patra, Goutam K
|Abstract:||Action of HCl on 1-(8'-amino-α-naphthyl)-4-(8'-amino-anaphthylamine)-1-azabuta-1 ,3-diene in aqueous methanol yields the mono hydrochloric acid salt of 1H-perimidine 1 as a dihydrate. A tentative mechanism for the reaction is proposed. The X-ray crystal structure of the salt has been determined. Neutralisation of an aqueous solution of the hydrochloride salt by a base generates 1, which has antitumor activities, in the free state.|
|Appears in Collections:||IJC-B Vol.41B(01) [January 2002]|
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.