Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/21776
Title: Solid phase synthesis of benzimidazole ketones and benzimidazole chalcones under solvent-free conditions
Authors: Dubey, P K
Kumar, C Ravi
Babu, Balaji
Issue Date: Dec-2003
Publisher: NISCAIR-CSIR, India
Abstract: Oxidation of 1-alkyl/aralkyl-2-(α-hydroxyalkyl/aryl)benzimidazoles 1 with KMnO4 on neutral alumina under solid phase conditions gives the corresponding ketones, 1-alkyl/aralkyl-2-acylbenzimidazoles 2. Compound 2a (R2 = CH3) on condensation with aromatic aldehydes in the presence of solid NaOH under solvent-free conditions, yields the corresponding chalcones, 1-alkyl/aralkyl-2-benzimidazole aryl vinyl ketone 3.
Page(s): 3128-3130
URI: http://hdl.handle.net/123456789/21776
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.42B(12) December 2003]

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