Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/21681
Title: Bridgehead nitrogen heterocyclic systems: Synthesis and evaluation of biological activity of 2,3-dihydrothiazolo[3',2':2,3]-as-triazino[5,6-b] indole and quinoxalino[2',3':4,5] thiazolo [3,2-b]indolo[2,3-e]-as-triazine and their isomeric systems
Authors: Mohan, Jag
Anupama
Issue Date: Aug-2003
Publisher: NISCAIR-CSIR, India
Abstract: 2,3-Dihydro-6-ethyl-5H-as-triazino[5,6-b]indole-3-thione 2, on condensation wit h 1,2-dibromoethane and 2,3-dichloroquinoxaline gives the cyclized products, 9-ethyldihydrothi azolo[3',2':2,3]-as-triazino[5,6-b]indole hydrobromide 4 and 11-ethyl quinoxalino[2', 3':4, 5]thiazolo[3, 2-b]indolo[2, 3-e]-as-triazine 6 respectively and not the angular isomers, 2, 3-dihydro-9-ethyl- 1H-[1, 3] thiazolo[2', 3':3, 4]-as-triazino[5, 6-b]indole hydrobromide 3 and 1 -ethylquinoxalino [2' , 3':4,5]thiazolo[2,3-c]indolo[2,3-e]-as-triazine 5. The unequivocal synthesis of the latter 3 and 5 has been accomplished by reaction of 7-Ethylisatin -3- thiosemicarbazone 1 with 1, 2-dibromoethane and 2,3-dichloroquinoxaline, respectively. The antibacterial and anti fungal activity of the synthesized compounds have also been evaluated.
Page(s): 2003-2005
URI: http://hdl.handle.net/123456789/21681
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.42B(08) [August 2003]

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