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Title: Synthesis of 4-thiazolidinones and 2-azetidinones bearing benzo (b) thiophene nucleus as potential antitubercular and antimicrobial agents
Authors: Thaker, K M
Kachhadia, V V
Joshi, H S
Issue Date: Jun-2003
Publisher: NISCAIR-CSIR, India
Abstract: Substituted 4-thiazolidinoncs 3a-1 have been prepared by the condensation of 2-(substituted-benzalhydrazinocarbonyl)-3,5-dichlorobcnzo(b)thiophene 2a-1 with thioglycolic acid. The synthesis of 2-azetidinones 4a-1 has been undertaken by the reaction of 2a-1 with chloroacetyl chloride in the presence of triethylamine. The structures of the compounds synthesised are assigned on the basis of elemental analysis, IR and 1H NMR spectral studies.
Page(s): 1544-1547
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.42B(06) [June 2003]

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