Please use this identifier to cite or link to this item:
Title: Synthesis of 6-aryl-2-(2-phenyl-1,8-naphthyridine-3-carbonyl)-4,5-dihydropyridazin- 3(2H)-ones
Authors: Mogilaiah, K
Kankaiah, G
Issue Date: Mar-2003
Publisher: NISCAIR-CSIR, India
Abstract: Condensation of 2-phenyl-1,8-naphthyridine-3-carboxylic acid hydrazide 1 with β-aroylpropionic acids 2 in ethanol affords the corresponding N-(2-phenyl-1,8-naphthyridine-3-carbonyl)-β-aroylpropionic acid hydrazones 3, which on treatment with gl. acetic acid undergo facile cyclization to yield 6-aryl-2-(2-phenyl 1,8-naphthyridine 3-carbonyl)-4,5-di hydro-pyridazin-3(2H)-ones 4. The compounds 4 have been tested for their antibacterial activity. The structures of the products have been delineated by elemental analyses and spectral studies.
Page(s): 658-660
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.42B(03) [March 2003]

Files in This Item:
File Description SizeFormat 
IJCB 42B(3) 658-660.pdf566.61 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.