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Title: Stereoisomeric synthesis of oxazolidinone and fused pyrrolidine derivatives via azomethine ylides and their antimicrobial activity
Authors: Pardasani, P
Pardasani, R T
Chaturvedi, V
Saxena, A
Issue Date: Feb-2003
Publisher: NISCAIR-CSIR, India
Abstract: The reaction of isatin with secondary cyclic α-amino acid 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid gives rise to azomethineylide which undergoes [3+2] cycloaddition with various dipolarophiles to afford inseparable stereoisomeric mixture of spiro oxazolidinone and fused pyrrolidine derivatives. The newly synthesized compounds have been screened for their antimicrobial activities.
Page(s): 412-415
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.42B(02) [February 2003]

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