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Title: Efficient synthesis of 1,2,4-triazolo[4,3-a][1,8]naphthyridines using nitrous acid under microwave irradiation
Authors: Mogilaiah, K
Prashanthi, M
Vidya, K
Issue Date: Dec-2004
Publisher: NISCAIR-CSIR, India
IPC Code: Int.Cl.7 C 07D 249/22
Abstract: A highly efficient, simple and rapid method for the synthesis of 1,2,4-triazolo[4,3-a][1,8] naphthyridines 8 by the oxidation of the corresponding aryl aldehyde 3-(p-nitrophenyl)-1, 8-naphthyridin-2-ylhydrazones 7 using nitrous acid (NaNO2/CH3COOH) under microwave irradiation has been described. Microwave assisted react ions have resulted in better yields or the desired products than prepared under conventional conditions. The structures of the compounds 3-8 are supported by spectral and analytical data.
Page(s): 2641-2645
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.43B(12) December 2004]

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