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Title: Synthesis of some new 4-O-(-β-D-glucopyranosyloxy)-4, 6-diaryl-tetrahydropyrimidine- 2-thiones and their biological activities
Authors: Ingle, V N
Kharche, S T
Upadhyay, U G
Issue Date: Sep-2004
Publisher: NISCAIR-CSIR, India
IPC Code: Int.Cl.7 C 07 D // A 61 P 31/04, 31/10
Abstract: 4-O-(-β-D-glucopyranosyloxy)-4, 6-diaryl-tetrahydropyrimidine-2-thiones have been synthes ized by the reaction of equimolar amounts of 2,3 ,4,6-tetra-O-acetyl-α-D-glycosyl bromide-1 via its potassium salt of 4'-hydroxy-4,6-diaryl-tetrahydropyrimidine-2-thione followed by catalytic deacetylation with CH3ONa in methanol. Products are characterized by FT-IR, 1H NMR, 13C NMR, FAB-MS, optical activity, elemental analysis and chemical properties.
Page(s): 2027-2031
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.43B(09) [September 2004]

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