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Title: Studies on biological evaluation of cyanopyrans and pyrazolines using microwave assisted synthesis
Authors: Kanjariya, H M
Radhakrishnan, T V
Ramchandran, K R
Parekh, Hansa
Issue Date: Jul-2004
Publisher: NISCAIR-CSIR, India
IPC Code: Int.Cl.7 C 07 D309/00
Abstract: A series of 3-cyanopyrans 3a-k and pyrazolines 4a-k have been synthesied by condensing 4'-(α-isopropyl-p-chlorophenylacetamidophenyl)-3-aryl-2-propen-1 -ones 2 with malononitrile and hydrazine hydrate respectively. Moreover, a simple and efficient method has been deviced for the rapid and improved synthesis of pyrazolines using microwave irradiation (MWI). All the products have been characterised by elemental analyses, IR, 1H NMR, mass spectral study and screened for their antimicrobial activity against several microbes and antitubercular activity against Mycobacterium tuberculosis H37 Rv.
Page(s): 1569-1573
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.43B(07) [July 2004]

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