Please use this identifier to cite or link to this item:
Title: Synthesis of chromene-2-thiones and in vitro evaluation of their antifungal and antibacterial activities
Authors: Devi, Nepram Sushuma
Singh, Thokchom Prasanta
Khumanthem, Nonibala
Singh, Okram Mukherjee
Keywords: β-Oxodithioester;Cupric chloride;Coumarin;Solvent free;Antimicrobial activity
Issue Date: Sep-2013
Publisher: NISCAIR-CSIR, India
Abstract: Cyclocondensation of β-oxodithioesters with substituted 2-hydroxy benzaldehydes in presence of copper(II)chloride as the catalyst yields 3-alkanoyl/aroyl/heteroaroyl-2H-chromene-2-thiones (87–95% yields). These reactions are carried out under solvent-free conditions. All the synthesized compounds have been evaluated for their antifungal and antibacterial activities using tube dilution technique. Only five compounds are found exhibiting good antifungal and antibacterial activities.
Page(s): 1224-1231
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.52B(09) [September 2013]

Files in This Item:
File Description SizeFormat 
IJCB 52B(9) 1224-1231.pdf94.58 kBAdobe PDFView/Open

Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.