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|Title:||Synthesis and characterization of some novel 4-formyl pyrazolylthiazoles of potential medicinal interest using Vilsmeier-Haack reaction|
|Authors:||Sharma, Pawan K|
Dhawan, S N
Singh, S P
|Abstract:||Two series of 4-formyl-1, 3-disubstituted pyrazoles namely 2-[3-(2,4-difluorophenyl)-4-formylpyrazol-l-yl]-6-substituted benzothiazoles (3) and 2-[3-(2,4-difluorophenyl)-4-formylpyrazol-lyl]-4-arylthiazoles (7) have been synthesized for evaluation of their antifungal activity through Vilsmeier-Haack reaction on hydrazones (2, 6) of 2,4-difluoroacetophenone with 2-hydrazino-6-substituted benzothiazoles (2) and 2-hydrazino-4-phenyll substituted phenylthiazoles (6). None of the compounds exhibit any significant antifungal activity.|
|Appears in Collections:||IJC-A Vol.41A(10) [October 2002]|
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