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Title: Structure/function studies of arsenite oxidoreductase and xanthine oxidase
Authors: Manikandan, Palanichamy
Ellis, Paul
Kuhn, Peter
Choi, Eun-Young
Hoffman, Brian
Hille, Russ
Issue Date: Jan-2002
Publisher: NISCAIR-CSIR, India
Abstract: The recently solved X-ray crystal structure of the molybdenum-containing arsenite ox idoreductase from Alcaligenes faecalis, is discussed, keeping in view the known mechanistic and spectroscopic information regarding the protein in a structural context. In addition, recent mechanistic studies of  xanthine oxidase are covered, with the conclusion that the reaction mechanism is initiated by nucleophilic attack of a Mo-OH group on substrate.
Page(s): 22-31
ISSN: 0975-0975(Online); 0376-4710(Print)
Appears in Collections:IJC-A Vol.41A(01) [January 2002]

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