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http://nopr.niscair.res.in/handle/123456789/2007| Title: | Studies on synthesis of unsymmetrical 2,2-bisbenzimidazole sulphides of pharmacological interest |
| Authors: | Dubey, P K Naidu, A Reddy, P V V Prasada Kumar, N D Mahesh Vineel, B George |
| Keywords: | Benzimidazole;Sulphides;TEA;TBAB;o-ethyl dithiocarbonate;TFA;Deoxy prazole |
| Issue Date: | Sep-2008 |
| Publisher: | CSIR |
| Abstract: | Condensation of 2-(-chloroethyl)benzimidazole 1 with benzimidazole-2-thiol 2 gives 2-(⍺-thioethyl-2-benzimidazolyl)benzimidazole 3. The latter can also be prepared by the reaction of 2-(⍺-thioethyl)benzimidazole 4 with 2-chlorobenzimidazole 5. Alternatively, 3 can also be synthesized by the independent condensation of o-phenylenediamine 7 respectively with 2-(s-⍺-ethyl-o-ethyldithio- carbonate)benzimidazole 6 and with 2-(⍺-thiopropionic acid) benzimidazole 8. The structures of all the compounds synthesized have been established on the basis of their spectroscopic data. |
| Page(s): | 1443-1446 |
| URI: | http://hdl.handle.net/123456789/2007 |
| ISSN: | 0376-4699 |
| Appears in Collections: | IJC-B Vol.47B(09) [September 2008] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 47(9) 1443-1446.pdf | 74.23 kB | Adobe PDF | View/Open |
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