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|Title:||New Curcumin - Bioconjugate: Synthesis and DNA Binding|
|Abstract:||A triglycyl derivative of curcumin, 1,7-bis (4-O-glycinoyl-3-methoxy phenyl)-1,6-heptadine-C-4-glycinoyl-3, 5-dione, was synthesized and characterized by UV, elemental analysis and 1H NMR. Interaction studies of curcumin and curcumin-bioconjugate with calf thymus DNA were carried out using UV -absorbance, gel electrophoresis and viscometric studies. Curcumin-bioconjugate was found to be A-T specific minOI- groove binder.|
|ISSN:||0975-0967 (Online); 0972-5849 (Print)|
|Appears in Collections:|| IJBT Vol.01(2) [April 2002]|
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