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Title: Claisen-Schmidt condensation in solvent-free conditions via the use of microwave irradiation and pestle/mortar
Authors: Mogilaiah, K
Chandra, A Vinay
Praveena, D
Keywords: Claisen-Schmidt condensation; , -unsaturated ketones;1,8-naphthyridine;Solid KOH;Solvent-free conditions;Microwave irradiation;Pestle;Mortar
Issue Date: Jul-2013
Publisher: NISCAIR-CSIR, India
Abstract: A high yielding and rapid method of Claisen-Schmidt condensation of 2-(4-acetylphenylamino)-3-(4-fluorophenyl)-1,8-naphthyridine 3 with various aromatic aldehydes in the presence of solid KOH in combination with microwave irradiation and also with a pestle and mortar under solvent-free conditions affords 2-(4-cinnamoylphenylamino)-3-(4-fluorophenyl)-1,8-naphthyridines (chalkones or , -unsaturated ketones) 4 is described.
Page(s): 949-952
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.52B(07) [July 2013]

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