NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Biochemistry and Biophysics (IJBB) >
IJBB Vol.45 [2008] >
IJBB Vol.45(3) [June 2008] >


Title: Alterations in immunoglobulins and cytokine levels in blood of malathion poisoning cases
Authors: Seth, Vandana
Banerjee, B D
Ahmed, Rafat S
Bhattacharya, A
Pasha, S T
Keywords: Malathion
Cytokines
Interleukins
Immunoglobulins
Pesticides
Issue Date: Jun-2008
Publisher: CSIR
Abstract: The excessive exposure and use of malathion, an organophosphate pesticide, has lead to deleterious effects on human health. Chronic exposure to organophosphates has been shown to suppress immune system in experimental animals. Therefore, in this study, we have investigated the immunoglobulins (IgG, IgM, IgE and IgA) and cytokines (IL-2, IL-4, IFN-ϒ and TNF-α) levels in blood of malathion poisoning cases, admitted in Guru Teg Bahadur Hospital (University of Delhi), Dilshad Garden, Delhi, India. All the seriously ill patients of malathion poisoning showed significant levels of residue (503-702 mg/L). While no significant changes were found in Igs levels in blood of malathion poisoning cases, there was a significant increase in IL-2, IL-4 and TNF-α levels in blood of malathion poisoning cases, and significant decrease in IFN-ϒ level, as compared to normal subjects. This study demonstrated altered levels of cytokines and interleukins in serum in response to malathion exposure.
Page(s): 209-211
ISSN: 0301-1208
Source: IJBB Vol.45(3) [June 2008]

Files in This Item:

File Description SizeFormat
IJBB 45(3) 209-211.pdf86.67 kBAdobe PDFView/Open
 Current Page Visits: 564 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 592961 since 06-Feb-2009  Last updated on 18-Sep-2014Webmaster: nopr@niscair.res.in