NISCAIR Online Periodicals Repository

Research Journals >
Indian Journal of Biochemistry and Biophysics (IJBB) >
IJBB Vol.45 [2008] >
IJBB Vol.45(3) [June 2008] >

Title: Protein translocation pathways across the inner and outer mitochondrial membranes
Authors: Kaur, Jaspreet
Kaul, Gautam
Keywords: Mitochondria
Membrane potential
ATP hydrolysis
Issue Date: Jun-2008
Publisher: CSIR
Abstract: Mitochondria import different proteins that are encoded by nuclear genes and synthesized in the cytosol. Separate translocases in inner and outer mitochondrial membranes like TOM, TIM23, TOB/SAM, TIM22 complex facilitate recognition, import and intramitochondrial sorting of preproteins. Various cytosolic factors as Hsp70 and auxillary factors assist in targeting these preproteins to their destinations. Also, different protein components in the matrix participate in this energetically driven translocation process in a reaction that depends upon membrane potential and matrix-ATP. This review summarizes the present knowledge on import and sorting of mitochondrial precursor proteins with glance on unresolved questions.
Page(s): 149-156
ISSN: 0301-1208
Source: IJBB Vol.45(3) [June 2008]

Files in This Item:

File Description SizeFormat
IJBB 45(3) 149-156.pdf319.8 kBAdobe PDFView/Open
 Current Page Visits: 67 
Recommend this item


Online Submission of Articles |  NISCAIR Website |  National Knowledge Resources Consortium |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2015 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 162375 since 01-Sep-2015  Last updated on 21-Jun-2016Webmaster: