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|Title:||Hepatoprotective effects of Liv-52 on ethanol induced liver damage in rats|
Gill, K D
|Abstract:||The mechanism of protective effects of Liv-52, a multiherbal hepatoprotective drug, on ethanol induced hepatic damage has been investigated. The results indicate that Liv-52 treatment prevents ethanol induced increase in the activity or the enzyme γ-glutamyl transpeptidase. Concomitantly there was also a decrease in ethanol accentuated lipid peroxidation in liver following Liv-52 treatment. The activity of antioxidant enzymes; superoxide dismutase, glutathione peroxidase and the levels of glutathione were decreased following ethanol ingestion. Liv-52 treatment was found to have protective effects on the activity of superoxide dismutase and the levels of glutathione. The results obtained from the study indicate hepatoprotective nature of Liv-52 which might be attributed to its ability to inhibit lipid peroxidation.|
|ISSN:||0975-1009 (Online); 0019-5189 (Print)|
|Appears in Collections:|| IJEB Vol.37(08) [August 1999]|
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