Please use this identifier to cite or link to this item:
|Title:||Expedient synthesis of 1,2,4-triazolin-3-one derivatives as DNA cleavage and antioxidant agents|
Kamble, Ravindra R
Kattimani, Pramod P
Belgur, Sudha S
|Abstract:||The present study involves the synthesis of fluoren-9-ylidene 5a-e and isoindolin-1,3-dione derivatives 5f-j appended to 1,2,4-triazolin-2-one under solvent and neat conditions. The title compounds have been evaluated for the extent of cell penetration through biological membranes (clogP) and drug score has been calculated and further screened for DNA cleavage and antioxidant activities.|
|Appears in Collections:||IJC-B Vol.52B(06) [June 2013]|
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.