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Title: Synthesis and insecticidal activity of some 1,3,4-oxadiazole derivatives containing phenoxyfluorophenyl group
Authors: Mohan, T P
Vishalakshi, B
Bhat, K S
Rao, K S
Kendappa, G N
Issue Date: Aug-2004
Publisher: NISCAIR-CSIR, India
IPC Code: Int.Cl.7 C 07 D 271/10
Abstract: The synthesis of a few 1,3,4-oxadiazoles 5a-e is described. 4- Fluoro-3-phenoxybenzoic acid 2 is prepared starting from 4-Fluoro-3- phenoxybenzaldehyde 1. Esterification of 2 with methanol in the presence of H2SO4 gives the corresponding ester 3. Hydrazinolysis of 3 with hydrazine hydrate results in acid hydrazide 4. Hydrazide on reaction with aryl acid chlorides in presence of POCl3 affords oxadiazoles 5a-e. The compounds 5b-e manifest low insecticidal activity against certain crop pests.
Page(s): 1798-1801
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.43B(08) [August 2004]

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