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Title: A simple and convenient synthesis of 4,6- disubstituted 3-cyanopyridin-2(1H)-ones under solvent-free microwave conditions
Authors: Dave, Chaitanya G
Shah, Dhaval A
Agrawal, Yadvendra K
Issue Date: Apr-2004
Publisher: NISCAIR-CSIR, India
IPC Code: Int.Cl.7 C 07 D 213/00
Abstract: A rapid and efficient method for the preparation of 4,6- disubstituted 3-cyanopyridin-2(1H)-ones by the reaction between 1, 3-diarylpropen-1-ones and cyanoacetamide using powdered potassium hydroxide under microwave irradiation is reported. Excellent yields and higher purity are obtained in this solvent free one pot synthesis as compared to conventional methods.
Page(s): 885-887
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections: IJC-B Vol.43B(04) [April 2004]

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