Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/1827
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dc.contributor.authorDas, Dhanjit Kumar-
dc.contributor.authorSaini, Mohini-
dc.contributor.authorSwarup, Devendra-
dc.contributor.authorGupta, Praveen Kumar-
dc.date.accessioned2008-08-11T10:58:39Z-
dc.date.available2008-08-11T10:58:39Z-
dc.date.issued2008-04-
dc.identifier.issn0972-5849-
dc.identifier.urihttp://hdl.handle.net/123456789/1827-
dc.description195-199en_US
dc.description.abstractInterleukin-18, a component of innate immunity with potent interferon-ϒ-inducing activity, is not well characterized in wild ruminants. In this study, IL-18 cDNA of Nilgai (Boselaphus tragocamelus) was cloned and characterized. The nucleotide sequence was 582 bp long and contained its entire open reading frame encoding 193 amino acid residues. The sequence analysis indicated seven nucleotide substitutions with reported buffalo sequence showing 98.5% similarity, 97.8% with cattle and 97.6% with sheep. The Nilgai IL-18 cDNA included a putative cleavage site of IL-1β-converting enzyme (ICE) and IL-1 signature-like sequence identified in human and cat IL-18 cDNA. Both nucleotide as well as amino acid sequence similarity shows that the cloned sequence was closer to buffalo IL-18 sequence.en_US
dc.language.isoen_USen_US
dc.publisherCSIRen_US
dc.sourceIJBT Vol.7(2) [April 2008]en_US
dc.subjectinerleukin-18en_US
dc.subjectBoselaphus tragocamelusen_US
dc.subjectCloningen_US
dc.subjectcDNA sequenceen_US
dc.subjectNilgaien_US
dc.titleComparison of nucleotide and amino acids sequence of Nilgai (Boselaphus tragocamelus) interleukin-18 (IL-18) with other ruminantsen_US
dc.typeArticleen_US
Appears in Collections: IJBT Vol.07(2) [April 2008]

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