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http://nopr.niscair.res.in/handle/123456789/18028| Title: | Green synthesis and antibacterial activity of 3-aryl-4-formyl-1-[3-(4-fluorophenyl)-1,8-naphthyridin-2-yl]pyrazoles |
| Authors: | Mogilaiah, K Chandra, A Vinay Srivani, N Praveena, D |
| Keywords: | 1,8-Naphthyridine;Pyrazole;Vilsmeier-Haack reagent;Solid support;Microwave irradiation;Antibacterial activity |
| Issue Date: | May-2013 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | An efficient and convenient method for the synthesis of 3-aryl-4-formyl-1-[3-(4-fluorophenyl)-1,8-naphthyridin-2-yl]-pyrazoles 4 from acetophenone 3-(4-fluorophenyl)-1,8-naphthyridin-2-ylhydrazones 3 is achieved using POCl3-DMF over silica gel under microwave irradiation. The structural assignments of compounds 3 and 4 are based on their elemental analyses and spectral (IR, 1H NMR and MS) data. The compounds 4 have been screened for their antibacterial activity. |
| Page(s): | 698-701 |
| URI: | http://hdl.handle.net/123456789/18028 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.52B(05) [May 2013] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 52B(5) 698-701.pdf | 66.86 kB | Adobe PDF | View/Open |
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