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|Title:||Development and Evaluation of Matrix and Two Layered Sustained Release Suppositories of Nimesulide|
Bandyopadhyay, A K
|Abstract:||Nimesulide loaded conventional suppositories, sustained release matrix suppositories and sustained realesed two layered suppositories were prepared using polyethyleneglycol (PEG) -4000 and ethylcellulose. In vitro characteristics of these suppositories were evaluated. In comparison to conventional suppositories the release of drug from sustained release matrix suppositories was gradual and extended over a period of time. On the other hand, two layered suppositories produced an initial quick release followed by ex tended release of drug.|
|ISSN:||0975-1084 (Online); 0022-4456 (Print)|
|Appears in Collections:||JSIR Vol.61(05) [May 2002]|
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