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Title: Development and Evaluation of Matrix and Two Layered Sustained Release Suppositories of Nimesulide
Authors: Ravi, M
Sa, B
Bandyopadhyay, A K
Issue Date: May-2002
Publisher: NISCAIR-CSIR, India
Abstract: Nimesulide loaded conventional suppositories, sustained release matrix suppositories and sustained realesed two layered suppositories were prepared using polyethyleneglycol (PEG) -4000 and ethylcellulose. In vitro characteristics of these suppositories were evaluated. In comparison to conventional suppositories the release of drug from sustained release matrix suppositories was gradual and extended over a period of time. On the other hand, two layered suppositories produced an initial quick release followed by ex tended release of drug.
Page(s): 366-369
ISSN: 0975-1084 (Online); 0022-4456 (Print)
Appears in Collections:JSIR Vol.61(05) [May 2002]

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