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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.47B [2008] >
IJC-B Vol.47B(07) [July 2008] >
| Title: | Cu(OTf)₂ catalyzed Biginelli type condensation of aldehydes, β-keto esters and carbamates: Synthesis of 3,4-dihydro[1,3]oxazin-2-ones |
| Authors: | Jagdale, Arun R
Paraskar, Abhimanyu S
Sudalai, Arumugam |
| Keywords: | Aldehydes
Catalysts
Multicomponent reaction
Copper |
| Issue Date: | Jul-2008 |
| Publisher: | CSIR |
| Abstract: | Cu(OTf)₂ catalyzes effectively a new multicomponent reaction comprising aldehydes, β-ketoester and methyl carbamate in acetonitrile to afford substituted 3,4-dihydro[1,3]oxazin-2-ones in 60-82% yields. These compounds have been found to show inhibition activity against HL-60 cancer cell. |
| Page(s): | 1091-1095 |
| ISSN: | 0376-4699 |
| Source: | IJC-B Vol.47B(07) [July 2008]
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