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Title: Cu(OTf)₂ catalyzed Biginelli type condensation of aldehydes, β-keto esters and carbamates: Synthesis of 3,4-dihydro[1,3]oxazin-2-ones
Authors: Jagdale, Arun R
Paraskar, Abhimanyu S
Sudalai, Arumugam
Keywords: Aldehydes;Catalysts;Multicomponent reaction;Copper
Issue Date: Jul-2008
Publisher: CSIR
Abstract: Cu(OTf)₂ catalyzes effectively a new multicomponent reaction comprising aldehydes, β-ketoester and methyl carbamate in acetonitrile to afford substituted 3,4-dihydro[1,3]oxazin-2-ones in 60-82% yields. These compounds have been found to show inhibition activity against HL-60 cancer cell.
Page(s): 1091-1095
ISSN: 0376-4699
Appears in Collections:IJC-B Vol.47B(07) [July 2008]

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